Saturday, April 9, 2011

First human stem cell guinea pig revealed

In the six months since scientists announced they had infused a drug made from human embryonic stem cells into a partially paralyzed patient’s spine, the identity of the recipient has been shrouded in secrecy.

Recently, rumors began circulating in Internet chat rooms that details about the closely guarded experiment were finally about to be revealed.

Now, a 21-year-old Alabama nursing student who was paralyzed from the chest down in a car crash in September has come forward to identify himself as the volunteer.

“I was the first patient,” Timothy J. Atchison of Chatom, Ala., said in a telephone interview with The Washington Post on Wednesday evening. “I’m doing well.”

Atchison, known as T.J. to his family and friends, was a student at the University of South Alabama College of Nursing when his car crashed on Sept. 25, which, Atchison noted, was the birthday of Christopher Reeve, the actor who suffered a devastating spinal cord injury.

After undergoing emergency treatment at a regional medical center, Atchison was transferred to the Shepherd Center in Atlanta, which specializes in spinal cord injuries, for rehabilitation. It was there that he agreed to let doctors inject him with the drug — more than 2 million cells made from stem cells into his spine, he said.

“I feel really good about everything,” Atchison said. “I’ve got a positive attitude. I’m trying to live life to the fullest right now.”

The experiment is the first carefully designed attempt to study an embryonic stem cell therapy. It is seen by supporters and opponents of embryonic stem cell research as potentially pivotal to the future of the research, which proponents say could revolutionize medicine and critics denounce as immoral.

The trial is primarily assessing safety, but doctors are also testing whether the cells restore sensation and movement.

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